Bioshock's Big Daddy!
Ryu and Mr. Bubbles seriously had it out in this poll. It went back and forth between those two with usually only a one vote difference. They were tied for a couple of days prior to the Sunday deadline but the Big Daddy took it from Ryu with 2 votes on the very last day. It kinda sucks actually because I expected a tie or Ryu to jump ahead and I finished the line art for Mario vs. Ryu because of that. But I did lay out Mario vs. Bioshock already so it's just a matter of putting pen on paper and then scanning and coloring.
And yes, the Little Sister is in it.
As for the Tetriminos (my vote) and the Pyro, well, I think I'll sandwich an (as of yet) undecided character after Ryu before I get to those.
There were nearly double the voters in this poll compared to my last so thank you all for taking the time to help me decide. With so many awesome characters still available, this is a great way for me to narrow it down.